What is XELJANZ/XELJANZ XR?

Quick Rheumatoid Arthritis (RA) Facts

If you have been diagnosed with moderate to severe rheumatoid arthritis (RA), you are not alone. Approximately 1.5 million adult Americans have RA. Learn about the role of inflammation and RA joint damage, and the impact of RA.

  • RA IS AN AUTOIMMUNE DISEASE

    The immune system mistakenly attacks the body’s own tissues, specifically the synovium. As a result, inflammation occurs, which can lead to pain and swelling in the joints. Most of the time, natural inflammatory processes help to clear out infections and help to heal wounds and other damage to the body. When the inflammation continues without having an infection or injury, it can become part of a disease process and, in some cases, can lead to joint damage.

  • THE EFFECTS OF RA CAN START EARLY

    For some people, destruction to your joints can begin as early as 3 months after the onset of RA symptoms, with most people developing joint damage within 2 years. However, there are treatment options available that may help stop further joint damage.

  • RA IS PROGRESSIVE

    RA symptoms and joint damage are likely to worsen over time (even on good days when your RA pain feels mild) if left untreated or undertreated. That makes it important to work with your doctor to continually track your RA symptoms and discuss treatment options.

  • LOSS OF PHYSICAL FUNCTION MAY OCCUR

    Studies have shown that difficulty completing common daily activities such as getting in and out of bed, or walking, can be caused by the inflammation and ongoing joint damage associated with moderate to severe RA.

MODERATE TO SEVERE RA CAN BE TREATED

With the effectiveness of today’s therapies, some experts believe that the goal of an RA treatment should be to maintain a lower level of disease activity by reducing RA symptoms and further damage to joints, and improving a person’s ability to complete common daily tasks. See how XELJANZ performed in clinical trials to help meet these kinds of treatment goals.

Learn from me, I was slow to tell my doctor that my RA symptoms were worsening and now it’s hard to do simple tasks like opening jars.-Patient with Moderate to Severe RA

Understanding Joint Damage

When considering how RA may impact the body, it’s important to recognize that no two people with RA are exactly alike. Some people with moderate to severe RA may find that their symptoms come and go, while others may experience swollen and achy joints on a daily basis. But even when your RA symptoms go unnoticed, inflammation from RA can still cause ongoing damage to your joints.

These images of potential disease progression are for illustrative purposes only, and are not intended to be fully anatomically accurate.

Learn About A Moderate to Severe RA Treatment That Can Help Reduce Further Joint Damage.