What is XELJANZ/XELJANZ XR?

Moderate To Severe Rheumatoid Arthritis (RA) Treatment Options

There are a number of ways to treat moderate to severe rheumatoid arthritis (RA). And while there’s no cure for RA, medication may help reduce the signs and symptoms of RA.

Here are some of the different types of treatments available to treat moderate to severe RA:

CORTICOSTEROIDS

Corticosteroids, also known as steroids, are used on a short-term basis to help with inflammation.

How they are prescribed
Pill or an injection into a muscle or directly into an affected joint.

NSAIDS

Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to help with joint pain and inflammation.

How they are prescribed
Pill

DMARDS

Disease-modifying antirheumatic drugs (DMARDs) work to reduce the body's overactive immune and/or inflammatory processes that cause RA symptoms such as joint pain and swelling.

The DMARD family can be classified as the following:

NON-BIOLOGIC DMARDS

Traditional non-biologic DMARDs, like methotrexate, are often prescribed at the time of diagnosis.

Oral synthetic small molecules, like Janus kinase (JAK) inhibitors are another class of non-biologic DMARDs. JAK inhibitors work by blocking JAK enzymes located within cells.

How they are prescribed
Pill or injection

XELJANZ/XELJANZ XR is a JAK inhibitor and available as an oral pill. Learn more about XELJANZ.

BIOLOGIC DMARDS

Biologic DMARDs are proteins manufactured using recombinant DNA technology. They are immunosuppressants that target and block the action of cells or chemicals that enable the immune system to cause inflammation and other symptoms of RA.

Types of biologic DMARDs include tumor necrosis factor (TNF) inhibitors and non-TNF inhibitors.

How they are prescribed
Injection or infusion

SURGERY

While surgery is not for everyone, it may be an important option for people with severe joint damage that limits joint function.

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